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The members of the neurotrophin family of growth factors, such as BDNF and NGF, play essential roles in the development of the nervous system, as they support the survival, growth, and maintenance of neurons in the brain [229]

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Lipid accumulation, gene/protein expression, and 5’ adenosine monophosphate-activated protein kinase (AMPK) signaling were assessed under lactate exposure, GPR81 knockdown, monocarboxylate transporter 1 (MCT1) inhibition, and AMPK activation conditions